Publications by authors named "P N Goldwater"

Article Synopsis
  • Recent research into Sudden Infant Death Syndrome (SIDS) suggests that metabolic acidosis and sepsis are significant factors, challenging the traditional brain-centered theories that have dominated the field for decades.
  • Analysis of various studies indicates that infections might play a crucial role, as many SIDS risk factors are tied to infection, which could lead to organ failure and respiratory issues in infants.
  • The paper advocates for including specific metabolic tests (like pH and bicarbonate levels) in autopsies of unexpected child deaths to better understand the underlying causes of SIDS.
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From the earliest publications on cot death or sudden infant death syndrome (SIDS) through to this day, clinical pathology and epidemiology have strongly featured infection as a constant association. Despite mounting evidence of the role of viruses and common toxigenic bacteria in the pathogenesis of SIDS, a growing school of thought featuring a paradigm based on the triple risk hypothesis that encompasses vulnerability through deranged homoeostatic control of arousal and/or cardiorespiratory function has become the mainstream view and now dominates SIDS research. The mainstream hypothesis rarely acknowledges the role of infection despite its notional potential role as a cofactor in the triple hit idea.

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Unlabelled: This paper presents a timely and constructive critique of mainstream SIDS research. It is concerning that twenty-first century medical science has not provided an answer to the tragic enigma of SIDS. The paper helps explain why this is so and illustrates possible shortcomings in the investigation of Sudden Infant Death Syndrome/Sudden Unexplained Infant Death (SIDS/SUID) by mainstream researchers.

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