Publications by authors named "P N Giannakopoulos"
Background: Court-ordered forensic psychiatry treatments (COT) are specifically designed to reduce the risk of violence in mentally disordered offenders. Given their high costs and ethical issues, mental health professionals need admission criteria to be able to select those candidates with optimal benefit. This study analyses offender-related and treatment-related determinants of COT outcome and risk mitigation.
View Article and Find Full Text PDFThis EEG study aims at dissecting the differences in the activation of neural generators between borderline personality disorder patients with court-ordered measures (BDL-COM) and healthy controls in visual perspective taking. We focused on the distinction between mentalizing (Avatar) and non-mentalizing (Arrow) stimuli as well as self versus other-perspective in the dot perspective task (dPT) in a sample of 15 BDL-COM cases and 54 controls, all of male gender. BDL-COM patients showed a late and diffuse right hemisphere involvement of neural generators contrasting with the occipitofrontal topography observed in controls.
View Article and Find Full Text PDFArticle Synopsis
- Amyloid-β plaques are a key indicator of Alzheimer's disease, and dual PET scans are used to assess both amyloid presence and glucose metabolism to aid in diagnosis.
- The study involved 166 participants across various cognitive states who underwent multiple imaging techniques, including innovative deep learning models to predict FDG PET results from early-phase amyloid scans.
- Results indicated a moderate clinical similarity score between synthetic and actual FDG PET scans, suggesting potential for reducing the number of scans while still accurately assessing neurodegeneration.
Introduction: Wide use of facemasks is one of the many consequences of the COVID-19 pandemic.
Methods: We used an established working memory n-back task in functional magnetic resonance imaging (fMRI) to explore whether wearing a KN95/FFP2 facemask affects overall performance and brain activation patterns. We provide here a prospective crossover design 3 T fMRI study with/without wearing a tight FFP2/KN95 facemask, including 24 community-dwelling male healthy control participants (mean age ± SD = 37.