Publications by authors named "P N Fru"
Article Synopsis
- Acute pancreatitis (AP) can be severe and unpredictable, and this study explored metabolic and lipoprotein profiles in AP patients of African descent to better understand its pathophysiology for improved prognosis and management.
- Serum samples from 30 AP patients of varying severity and 9 healthy controls were analyzed using nuclear magnetic resonance spectroscopy to identify metabolic signals and lipoprotein characteristics.
- Key findings showed that increased levels of certain metabolites (3-hydroxybutyrate, acetoacetate) and decreased ascorbate correlate with AP severity, while lipid profiles differ from healthy controls, suggesting that these metabolic indicators can help differentiate AP states and inform treatment decisions.
Ownership, coverage, utilisation and maintenance of long-lasting insecticidal bed nets in three Health Districts in Cameroon: a cross-sectional study.
Pan Afr Med J
October 2024
Introduction: the Bamenda, Santa and Tiko Health Districts are in the highest malaria transmission strata of Cameroon. The purpose of this study was to explore the indicators of ownership and utilisation as well as maintenance of Long-Lasting Insecticidal Nets (LLINs) in three health districts in Cameroon.
Methods: a cross-sectional household survey involving 1,251 households was conducted in the Tiko Health District (THD) in June and July 2017 and in Bamenda and Santa Health Districts in March to May 2018.
Background: Pancreatic Ductal Adenocarcinoma (PDAC) is an aggressive cancer characterized by an immunosuppressive microenvironment. Patients from specific ethnicities and population groups have poorer prognoses than others. Therefore, a better understanding of the immune landscape in such groups is necessary for disease elucidation, predicting patient outcomes and therapeutic targeting.
View Article and Find Full Text PDFBackground: Violent interpersonal acts account for a large proportion of unnatural deaths in South Africa. A significant proportion of unnatural deaths are due to penetrating thoracic trauma and preventable haemorrhage. Current indications for emergent thoracotomy are unreliable.
View Article and Find Full Text PDFBackground: Thyroid cancer is prevalent both internationally and locally, and is the most common cause of endocrine malignancies in Africa. The prognosis of thyroid cancer in general is quite good, but to achieve good outcomes, appropriate methods for diagnosis are important. A cytology result obtained from a fine needle aspiration and biopsy (FNAB) is one such method, and is less invasive and has less risk compared with obtaining a histological result via open surgery.
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