Publications by authors named "P N Colombini"

Despite ongoing efforts to enhance diagnostic and treatment processes, the success rate for eradicating infections, particularly prosthetic joint infections (PJIs), currently stands at around 50%. For acute infections occurring shortly after arthroplasty, guidelines recommend a treatment known as DAIR (debridement, antibiotics, and implant retention). This approach is suggested for infections within 30 days post-arthroplasty or with less than 3 weeks of symptoms, provided that there is a stable implant and adequate soft-tissue mass.

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The aim of this study was to compare treatment adherence and tolerability of different lithium formulations in 70 bipolar patients receiving lithium therapy for the first time. During the 1-year follow-up, information was collected regarding patient's clinical course, therapeutic adherence, side effects of the treatment and serum levels of lithium, creatinine and thyroid-stimulating hormone. At baseline, 30 patients (43%) were on prolonged-release lithium formulations and 40 (57%) on immediate-release formulations.

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Article Synopsis
  • Emotional dysregulation is a key factor in understanding the overlap between ADHD and cyclothymia, with the study aiming to assess how often these conditions occur together and identify demographic and clinical differences.
  • Out of 165 outpatients studied, different groups were formed: 80 with ADHD, 60 with cyclothymic disorder, and 25 with both, revealing that cyclothymic patients were typically older and more often female.
  • The study found that ADHD patients had lower educational levels and higher rates of substance use, while non-comorbid cyclothymic patients experienced more panic disorder and higher risks of depression and suicide attempts compared to those solely with ADHD.
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This study aims to explore the relationships between delayed sleep phase disorder (DSPD) and emotional dysregulation in 240 patients (134 with cyclothymia, 81 with attention deficit hyperactivity disorder [ADHD] and 25 with both conditions). DSPD was assessed using the Morningness-Eveningness Questionnaire, followed by a clinical evaluation. Affective temperaments and emotional dysregulation were also investigated through the brief version of the Temperament Evaluation of Memphis, Pisa, Paris, and San Diego and the Reactivity, Intensity, Polarity, Stability questionnaires, respectively.

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