Publications by authors named "P Mur"
Radiographic findings in dogs with 360 degrees gastric dilatation and volvulus.
Vet Radiol Ultrasound
January 2025
Article Synopsis
- GDV (Gastric dilatation and volvulus) is a serious medical emergency in dogs, and this study aimed to analyze its radiographic features and how accurately different radiologists can diagnose it.
- The study found that the sensitivity of radiographs to detect 360-GDV was relatively low (43.7%-50%), while the specificity was higher (84.6%-92.1%), indicating some challenges in accurately diagnosing this condition.
- Key radiographic signs unique to 360-GDV included severe esophageal distension and the absence of small intestine swelling, but diagnosing it can be complicated due to similarities with other conditions like gastric dilatation (GD).
Objective: To study the fertility outcomes of women who tried to conceive after breast cancer (BC) treatment and fertility preservation.
Design: Retrospective observational, bicentric cohort study.
Setting: University hospital.
Constitutional heterozygous pathogenic variants in the exonuclease domain of POLE and POLD1, which affect the proofreading activity of the corresponding polymerases, cause a cancer predisposition syndrome characterized by increased risk of gastrointestinal polyposis, colorectal cancer, endometrial cancer and other tumor types. The generally accepted explanation for the connection between the disruption of the proofreading activity of polymerases epsilon and delta and cancer development is through an increase in the somatic mutation rate. Here we studied an extended family with multiple members heterozygous for the pathogenic POLD1 variant c.
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