Publications by authors named "P Morgagni"
Gastric cancer is a significant health concern worldwide, and its diagnosis and management are of paramount importance. Ectopic pancreas (EP) refers to an embryological abnormality where healthy pancreatic tissue develops without anatomical, vascular, or neural communication with the normal pancreas. We report the case of a patient whose initial endoscopic evaluation suggested early gastric cancer, but computed tomography scan (CT scan) and endoscopic ultrasound (EUS) indicated a locally advanced tumor.
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- * It involved surgical samples from EGC patients with a 10-year follow-up, using specialized genomic panels to examine molecular characteristics and pathway instability scores.
- * Key findings indicated that the aggressive Pen A subtype has more ARID1A mutations and greater genetic instability, while LRP1B alterations were linked to a higher risk of relapse or death, suggesting potential markers for prognosis in EGC patients.
Background: Radical gastrectomy remains the main treatment for gastric cancer, despite its high mortality. A clinical predictive model of 90-day mortality (90DM) risk after gastric cancer surgery based on the Spanish EURECCA registry database was developed using a matching learning algorithm. We performed an external validation of this model based on data from an international multicenter cohort of patients.
View Article and Find Full Text PDFThe incidence of gastric cancer (GC) is expected to increase to 1.77 million cases by 2040. To improve treatment outcomes, GC patients are increasingly treated with neoadjuvant chemotherapy (NAC) prior to curative-intent resection.
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