Publications by authors named "P Mikosch"

Article Synopsis
  • The combination of pancreatitis, panniculitis, and polyarthritis (PPP) is a rare syndrome linked with pancreatitis or pancreatic cancers, highlighted by a case of a 50-year-old man who experienced worsening polyarthritis and nodules on his legs.
  • Lab tests confirmed pancreatitis, and a dermatological assessment established panniculitis, leading to the diagnosis of PPP.
  • Initial treatments with glucocorticoids and NSAIDs were ineffective, but after performing endoscopic retrograde cholangiopancreatography (ERCP) to remove blockages in the pancreatic duct, the patient's symptoms improved significantly, emphasizing the need for multidisciplinary awareness and management of this condition.
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Hashimoto's thyroiditis (HT), also known as chronic lymphocytic thyroiditis, is a frequent disorder of the thyroid gland caused by autoimmune-trigged lymphocytic infiltration and destruction of the thyroid gland. With the progressive destruction of the organ, the thyroid gland shrinks in size, thus commonly leading to hypothyroidism. Therapy of HT is mainly focused on managing the thyroid dysfunction by oral substitution of L‑thyroxine.

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In January 2019, a 30-year-old woman admitted to our inpatient department presented with undulating fever, pain in several joints, and significantly elevated liver enzymes and lactate dehydrogenase. After extended examination, infection with Brucella melitensis with liver, musculoskeletal, and pulmonary involvement was diagnosed and treated. Diagnosis was based on clinical examination, laboratory findings including seroconversion as a proof of immune response, magnetic resonance imaging, three-phase bone scintigraphy, and F‑18 FDG-PET (F-18 Flourdeoxyglucose positron emission tomography) illustrating the bone involvement and its normalization upon treatment.

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