Publications by authors named "P Meroni"

Autoimmune glomerulonephritis is a homogeneous area of renal pathology with clinical relevance in terms of its numerical impact and difficulties in its treatment. Systemic lupus erythematosus/lupus nephritis and membranous nephropathy are the two most frequent autoimmune conditions with clinical relevance. They are characterized by glomerular deposition of circulating autoantibodies that recognize glomerular antigens.

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Article Synopsis
  • - The collaboration between the authors and Professor Shoenfeld's group began in the late 80s, focusing on the anti-phospholipid syndrome (APS) and its underlying mechanisms.
  • - Their studies identified β2 glycoprotein I (β2GPI)-dependent antibodies as key factors that disrupt endothelial function, which is crucial to APS's development.
  • - Recent research has expanded to explore parallels between APS and COVID-19, enhancing understanding through animal models and further studies on endothelial behavior in both conditions.
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Article Synopsis
  • Value-based healthcare (VBHC) focuses on maximizing patient value and outcomes while minimizing costs, shifting the emphasis from the volume of services to the quality of care delivered.
  • This study evaluated the impact of a VBHC-principled preoperative evaluation at Humanitas Research Hospital by comparing results from 2019 (preintervention) to 2021 (postintervention).
  • The findings showed a significant reduction in preoperative tests and evaluation time, leading to lower healthcare costs without negatively affecting patient outcomes.
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