Publications by authors named "P Mathews"
Define microbiological characteristics of pathogens causing lower urinary tract infections (LUTI), frequency of (CT) or (GC), and accuracy of self-diagnosis by college women with LUTI symptoms. Sexually active women with LUTI symptoms attending a large south-eastern university. Participants completed a 15-question Qualtrics™ survey, provided urine for urinalysis and culture and a self-collected vaginal swab for CT/GC testing.
View Article and Find Full Text PDFPhase transformations and crystallographic defects are two essential tools to drive innovations in materials. Bulk materials design via tuning chemical compositions is systematized using phase diagrams. It is shown here that the same thermodynamic concept can be applied to manipulate the chemistry at defects.
View Article and Find Full Text PDFArticle Synopsis
- Dysfunction in the endolysosomal system is a key characteristic of Alzheimer's disease (AD), particularly due to the hyperactivity of the rab5 protein, impacting neuronal function.
- Researchers created a mouse model that over-expresses APPL1, a protein involved in regulating rab5 activity, leading to enlarged early endosomes and increased synaptic endocytosis.
- The study found that elevated levels of APPL1 resulted in negative effects on memory and synaptic function, emphasizing the role of endosomal dysregulation in the development of AD-related changes in neurons.*
Background: Hypertension is one of the most prevalent chronic diseases in the United States and can increase a person's risk of stroke and other cardiovascular complications. Yet only 1 in 4 people with high blood pressure in the United States have their blood pressure managed. To improve hypertension control, we supported 9 health centers in Texas with the implementation of the Healthy Heart Ambassador Blood Pressure Self-Monitoring (HHA) Program.
View Article and Find Full Text PDFObjective: To assess the feasibility of using artificial intelligence (AI) to improve readability of online cataract surgery patient education materials (PEMs) in English and Spanish.
Participants: Websites with information dedicated to educating patients about cataract surgery.
Design: Comparative cross-sectional study.