Publications by authors named "P Mascarenhas"
Article Synopsis
- The systematic review analyzed HIV drug resistance in Mozambique, finding significant levels of resistance mutations in drug-naive and ART-experienced individuals, particularly to NNRTIs and NRTIs.
- Drug resistance mutations were more prevalent in the region of Beira and among pediatric patients compared to adults and pregnant women.
- The study emphasizes the need for ongoing surveillance and targeted interventions to improve ART regimens and public health strategies, particularly for vulnerable populations.
Article Synopsis
- Dental adhesives are crucial in modern restorative dentistry, but issues like secondary caries due to bacterial infiltration remain a challenge.
- The study evaluated natural antibacterial compounds in dental adhesives, aiming to find effective options that are safe and maintain adhesive integrity based on systematic review guidelines.
- Most reviewed studies indicated that using lower concentrations of natural agents can provide strong antibacterial effects without compromising adhesive properties, while higher concentrations can negatively affect the adhesive's performance.
Objectives: This study aims to evaluate the cytotoxicity and genotoxicity of three different extracts obtained from Filtek™ One Bulk Fill, Tetric Evoceram® Bulk Fill and Coltene Fill-Up! resins.
Materials And Methods: The cytotoxicity was determined on 3T3 fibroblast cells using the MTT and crystal violet assays. The genotoxicity was determined using a cytokinesis-block micronucleus assay.
Dementia is a rising public health concern. Feeding and nutritional problems increase as the disease progresses, affecting the clinical course and caregiver burden. While some guidelines advise against percutaneous endoscopic gastrostomy (PEG) and tube feeding in advanced dementia, conflicting evidence exists.
View Article and Find Full Text PDFFor percutaneous endoscopic gastrostomy (PEG)-fed head and neck cancer (HNC) patients, risk markers of poor outcomes may identify those needing more intensive support. This retrospective study aimed to evaluate markers of poor outcomes using TNM-defined stages, initial anthropometry [body mass index (BMI), mid-upper arm circumference (MUAC), tricipital skinfold (TSF), mid-arm muscle circumference (MAMC)] and laboratory data (albumin, transferrin, cholesterol), with 138 patients, 42-94 years old, enrolled. The patients had cancer, most frequently in the larynx ( = 52), predominantly stage IV ( = 109).
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