Publications by authors named "P Mas-Serrano"
Cassia angustifolia is a species of plant from the Senna family that has traditionally been used as a laxative in different herbal products and commercial medicines. Even though there are few documented drug-plant interactions, the use of C. angustifolia with different drugs may have additive effects, such as with other laxatives or potassium-depleting diuretics.
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- - Adalimumab is a monoclonal antibody used to treat inflammatory bowel disease (IBD), but its effectiveness can vary, making it important to personalize dosing.
- - A study developed two population pharmacokinetic (PopPK) models based on existing literature to improve dosing in IBD patients, using data from 54 patients.
- - Among the models, the one incorporating informative priors performed better, showing less bias and imprecision, and providing greater clinical impact compared to the basic estimated model and the reference model.
Introduction: To assess the efficacy and safety of high-flow nasal cannula (HFNC) in elderly patients with acute respiratory failure (ARF) not due to COVID-19, refractory to treatment with conventional oxygen therapy and/or intolerant to noninvasive ventilation (NIV) or continuous positive airway pressure (CPAP) and without criteria for admission to intensive care units (ICU).
Methods: Prospective observational study of patients with ARF treated with HFNC who presented clinical and arterial blood gas deterioration after 24 h of medical treatment and oxygenation by conventional systems. The degree of dyspnoea, gas exchange parameters (arterial O pressure/inspired O fraction ratio (PaO/FiO); oxygen saturation measured by oximetry/ inspired fraction of oxygen (Sp0/Fi0), ROX index), degree of patient tolerance and mortality were evaluated.
Background: Post-transplant lymphoproliferative disorders represent rare but serious complications of kidney transplantation.
Methods: We assessed incidence, risk factors, and outcomes in 21,546 patients receiving grafts between 1990 and 2009. Data were compared by decade of transplant (1990-1999 vs 2000-2009).