Womens Health (Lond)
January 2025
Introduction: Osteogenesis imperfecta (OI) is a rare genetic bone disorder, mainly caused by autosomal dominant mutations of the COL1A1 or COL1A2 genes that encode the alpha chains of type 1 collagen. In severe forms and in nonambulatory patients, for whom physical exercise is difficult, exposing the bone to mechanical stimuli by promoting movement, especially with physiotherapy and mobility aids, is an essential part of clinical practice. However, the effects of mechanical stimulation at the cellular level remain unknown for this disease.
View Article and Find Full Text PDFThe initial approach to soft tissue tumors in children and teenagers is everyone's responsibility. While the vast majority is benign, all practitioners dread missing a malignant lesion. The first step involves taking the patient's history and performing a clinical examination.
View Article and Find Full Text PDFWe report the first successful pediatric cochlear implantation in bilateral persistent stapedial artery (pSA) in India. Another child with unilateral pSA, the contralateral side was initially implanted. Both children were preoperatively diagnosed.
View Article and Find Full Text PDFPurpose: The aim of this study was to report on mid- to long-term results following large humeral tumoral resection and reconstruction with the induced-membrane technique in skeletally immature patients suffering from primary malignant bone tumours.
Methods: A retrospective analysis identified all children who underwent the two stages of a humeral reconstruction using the induced-membrane technique for primary malignant humerus tumours between 2002 and 2020. Functional assessment was conducted by an independent observer using the Musculoskeletal Tumor Society (MSTS) scoring system for the upper limb.