Publications by authors named "P Martin-Rabadan"
spp. colonization: a genotype source found in blood cultures that can become widespread.
Front Cell Infect Microbiol
November 2024
Objective: Our previous genotyping studies suggest that some anatomical locations act as reservoirs of genotypes that may cause further candidemia, since we found identical genotypes in gastrointestinal tract or catheter tip isolates and blood cultures, in contrast, we did not find blood culture genotypes in vagina samples. We observed that some genotypes can be found in blood cultures more frequently than others, some of them being called widespread genotypes because have been found in unrelated patients admitted to different hospitals. The presence of widespread genotypes may be more frequently found because of their predisposition to cause candidemia.
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- The COVID-19 pandemic led to a noticeable increase in catheter-related bloodstream infections (C-RBSI) at a large hospital, prompting the need to assess trends and causes over a five-year period from 2018 to 2023.
- A total of 556 C-RBSI episodes were analyzed, revealing fluctuating incidence rates, with the peak occurring during the pandemic year of 2020, and a slight decline in subsequent years.
- The study found that most C-RBSI cases were linked to coagulase-negative Staphylococci, but there was a significant increase in infections caused by Gram-negative bacteria post-pandemic.
Article Synopsis
- The study focuses on diagnosing catheter-related bloodstream infections (C-RBSIs) using the differential time to positivity (DTTP) technique, which helps identify if infections are linked to catheters.
- Out of 89 catheter blood cultures analyzed, only 9% were classified as C-RBSI, while over half were categorized as non-C-RBSI, suggesting many bacteremia cases were not catheter-related.
- The findings indicate that most catheters were not removed, leading to challenges in confirming if the infections were catheter-related through catheter-tip cultures, highlighting the need for further research into the effectiveness of the DTTP technique.
Article Synopsis
- The study investigates the prevalence of Trypanosoma cruzi infection (Chagas disease) among pregnant migrants in Madrid, focusing on their countries of origin and the effectiveness of screening methods.
- Conducted across eight hospitals between 2011 and 2016, it found that out of 149,470 deliveries, only 11,048 pregnant women were screened, with a significant majority being from Bolivia and a high prevalence of infection among those screened.
- Results highlighted a 47% average screening coverage across hospitals, showing a stark contrast between those with universal screening (73% coverage) versus selective screening (10% coverage), providing essential insights for health policymakers.
pneumonia (PJP) in immunocompromised patients entails high mortality and requires adequate laboratory diagnosis. We compared the performance of a real time-PCR assay against the immunofluorescence assay (IFA) in the routine of a large microbiology laboratory. Different respiratory samples from HIV and non-HIV-infected patients were included.
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