Publications by authors named "P Marnila"
Baltic herring is the main catch in the Baltic Sea; however, its usage could be improved due to the low processing rate. Previously we have shown that whole Baltic herring hydrolysates (BHH) and herring byproducts hydrolysates (BHBH) by commercial enzymes consisted of bioactive peptides and had moderate bioactivity in in vitro dipeptidyl peptidase (DPP)-4 assay. In this study, we identified the hydrolysate peptides by LC-MS/MS and predicted the potential bioactive DPP-4 inhibitory peptides using in silico tools.
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- - The study investigates how exposure to different types of soil—autoclaved (sterilized) and live—affects the immune system in mice, addressing the broader context of how lack of microbial diversity may contribute to immune disorders.
- - Both types of soil exposure led to immune system changes, with autoclaved soil increasing certain immune markers in the colon, while live soil boosted a specific immune response linked to type 1 inflammation and reduced other markers in the lymph nodes.
- - The findings suggest that neither soil type is harmful, and that live soil may help modulate immune responses beneficially, prompting further research on its effects in conditions associated with type 2 inflammation.
Introduction: The APOE ε4 allele predisposes to high cholesterol and increases the risk for lifestyle-related diseases such as Alzheimer's disease and cardiovascular diseases (CVDs). The aim of this study was to analyse interrelationships of APOE genotypes with lipid metabolism and lifestyle factors in middle-aged Finns among whom the CVD risk factors are common.
Methods: Participants (n = 211) were analysed for APOE ε genotypes, physiological parameters, and health- and diet-related plasma markers.
Article Synopsis
- The APOE ε4 allele is linked to increased risks of cardiovascular diseases and Alzheimer’s compared to ε3 and ε2 alleles.
- The study involved 188 Finnish volunteers to assess how personal genetic risk information and dietary/lifestyle guidance motivate healthier living, dividing participants into intervention and control groups based on their APOE status.
- The intervention resulted in improved dietary habits and reduced unhealthy food consumption, particularly among ε4 carriers, leading to measurable changes in key blood markers and health indicators.
Edible insect rearing could provide one alternative for protein production by having a smaller environmental impact than traditional livestock farming due to insects' ability to convert organic side streams. Currently, the insect rearing industry utilizes soybeans as a major source of protein in the feeds. Protein-rich by-products of food industry could be used to replace them in insect feeds, but it is not known if they also meet the insects' nutritional requirements.
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