Publications by authors named "P Marcos"
The urge to adopt cleaner technologies drives the search for novel and sustainable materials such as Hydrophobic Natural Deep Eutectic Solvents (HNADESs), a new class of green solvents characterized by their low toxicity, biodegradability, and tunable properties, aiming to be applied in various fields for handling non-polar substances. In this work, the solubilization of hydrocarbons in type V HNADESs (non-ionic organic molecules) formed by mixing carvone, a natural monoterpenoid, with organic acids (hexanoic to decanoic acids) is examined by applying both experimental and theoretical approaches. The synthesis and physicochemical characterization of different HNADESs allowed us to tailor their properties, aiming for optimal interactions with desired hydrocarbons.
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- COVID-19 led to a global pandemic in 2020, creating a need for efficient decision-making by medical staff with limited resources during healthcare emergencies.
- The study introduces an automated method that utilizes multimodal data fusion, combining clinical features and deep learning from chest X-ray images, to estimate the risks of hospitalization and mortality for COVID-19 patients.
- Results indicate high accuracy in risk assessment (AUC-ROC scores of 0.8452 and 0.8285 for hospitalization and mortality, respectively) and show that incorporating imaging features improves hospitalization risk evaluation, while clinical features are more critical for mortality, emphasizing the approach's potential to enhance clinical decision-making across various medical scenarios.
Recent Advances in Calixarene-Based Fluorescent Sensors for Biological Applications.
Sensors (Basel)
November 2024
Article Synopsis
- Calixarenes, a type of macrocyclic compound, have been combined with various fluorophores to create fluorescent probes for a wide range of applications, particularly in biological fields.
- The review highlights advancements in calixarene-based fluorescent sensors since 2009, focusing on their ability to detect important biological ions and specific biomolecules like amino acids and drugs.
- Additionally, the review discusses the role of calixarene-containing nanoparticles and nanoaggregates in imaging and drug delivery, while offering conclusions and future insights into the development of these technologies.
Article Synopsis
- The study aimed to summarize the epidemiological characteristics of severe community-acquired pneumonia (SCAP) in children under 15 years old admitted to hospitals in Shihezi, Xinjiang, China during 2023.
- A total of 309 cases were included, with organized data collection on patient demographics and respiratory samples analyzed for various pathogens using advanced sequencing methods.
- Results indicated a higher prevalence of SCAP cases in autumn and identified key pathogens, including Mycoplasma pneumoniae and respiratory syncytial virus, highlighting the infection's impact on different age groups.
Ten take-home messages on vasopressin use in critically ill patients.
Med Intensiva (Engl Ed)
December 2024
The most used vasopressors in critically ill patients are exogenous catecholamines, mainly norepinephrine. Their use can be associated with serious adverse events and even increased mortality, especially if administered at high doses. In recent years, the addition of vasopressin has been proposed to counteract the deleterious effects of high doses of catecholamines (decatecholaminization) with the intention of improving the prognosis of these patients.
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