Publications by authors named "P Marchese"
Article Synopsis
- - Melanoma cases are on the rise, leading to frequent updates in guidelines for diagnosis, staging, and treatment; recent approvals now include adjuvant therapy for stage IIb/c melanoma.
- - A study involving 92 melanoma patients revealed that those with stage IIb/c have a later age of diagnosis and a higher occurrence of specific characteristics like ulceration and angiotropism compared to stage IIIa patients.
- - While not statistically significant, stage IIb/c patients showed a higher rate of metastasis over a 5-year period (15%) compared to those with stage IIIa melanoma (4%), highlighting the potential benefits of adjuvant immunotherapy for stage IIb/c patients.
Article Synopsis
- Fungal signaling pathways play a significant role in how fungi communicate and respond to their environment, making them a key focus in biomaterial engineering.
- This review discusses the complexity of these biochemical and electrical signaling networks, including the structural aspects like hyphal structure and the challenges in studying them.
- The potential applications of understanding these pathways range from creating sustainable materials to developing biomonitoring systems, with a vision for using fungal signaling in future living composites.
Background: Immune checkpoint inhibitors (ICIs) are standard treatments for advanced solid cancers. Resistance to ICIs, both primary and secondary, poses challenges, with early mortality (EM) within 30-90 days indicating a lack of benefit. Prognostic factors for EM, including the lung immune prognostic index (LIPI), remain underexplored.
View Article and Find Full Text PDFBackground: Echocardiographic myocardial work is a new load-independent echocardiographic technique to quantify left ventricle (LV) systolic performance. Our aim was to establish normal values for echocardiographic myocardial work in a large population of healthy children.
Methods: For all the subjects 4-, 2-, and 3-chamber-view videos were stored.