Publications by authors named "P Mantilla"
Hypothalamic gliomas, though rare, present significant challenges in neuro-oncology due to their critical location and high morbidity risk. Pilocytic astrocytoma is the most common subtype, requiring a delicate balance between tumor control and preservation of neurological function. This study explores radiosurgery as a viable treatment option for hypothalamic gliomas, with a focus on low-grade lesions.
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- A supraorbital keyhole craniotomy (SOKC) offers a new method for accessing brain tumors and aneurysms in the front of the skull, but is not suitable for all patients due to potential complications.
- Researchers analyzed two cases involving the use of augmented reality (AR) and virtual reality (VR) to assist in choosing suitable patients and planning surgeries for removing meningiomas using the SOKC method.
- Results showed both patients successfully had their tumors removed with the SOKC approach, but faced some postoperative complications, emphasizing the need for careful patient selection and customized planning to improve outcomes using AR/VR technology.
Objective: Determine the prevalence of metabolic abnormalities (MA) and estimate the 10-year risk for cardiovascular disease (CVD) among Latin American HIV-infected patients receiving highly active anti-retroviral therapy (HAART).
Methods: A cohort study to evaluate MA and treatment practices to reduce CVD has been conducted in seven Latin American countries. Adult HIV-infected patients with at least one month of HAART were enrolled.
Serum hepatitis B virus (HBV) DNA level is a predictor of the development of cirrhosis and hepatocellular carcinoma in chronic hepatitis B patients. Nevertheless, the distribution of viral load levels in chronic HBV patients in Brazil has yet to be described. This cross-sectional study included 564 participants selected in nine Brazilian cities located in four of the five regions of the country using the database of a medical diagnostics company.
View Article and Find Full Text PDFIn the last few years the clinical need for HLA genotyping has become evident. However, the routine use of PCR-based DNA typing techniques has been hampered by economical and/or technical considerations. The classical PCR-SSO (product-dot) method has been widely tested and proven to be useful for large-scale HLA DNA typing.
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