Publications by authors named "P Mansoori"
Background: COVID-19 is known to be associated with increased risks of cognitive and psychiatric outcomes after the acute phase of disease. We aimed to assess whether these symptoms can emerge or persist more than 1 year after hospitalisation for COVID-19, to identify which early aspects of COVID-19 illness predict longer-term symptoms, and to establish how these symptoms relate to occupational functioning.
Methods: The Post-hospitalisation COVID-19 study (PHOSP-COVID) is a prospective, longitudinal cohort study of adults (aged ≥18 years) who were hospitalised with a clinical diagnosis of COVID-19 at participating National Health Service hospitals across the UK.
Human papillomavirus (HPV)-positive oropharyngeal carcinoma is a distinct type of head and neck carcinoma with improved prognosis. p16 immunostaining is often used as a surrogate marker for HPV infection in this particular setting. The aim of this study is to estimate the prevalence of p16 staining and HPV infection in head and neck sarcomatoid carcinomas as well as head and neck sarcomas.
View Article and Find Full Text PDFBackground: Wound debridement improves healing in a variety of acute and chronic ulcers. However, there is concern that debridement may trigger pathergy and worsen pyoderma gangrenosum (PG).
Objective: To determine whether published evidence supports conservative wound debridement for PG.
A proportion of patients infected with severe acute respiratory syndrome coronavirus 2 experience a range of neuropsychiatric symptoms months after infection, including cognitive deficits, depression and anxiety. The mechanisms underpinning such symptoms remain elusive. Recent research has demonstrated that nervous system injury can occur during COVID-19.
View Article and Find Full Text PDFArticle Synopsis
- Post-COVID cognitive deficits, often described as 'brain fog', are commonly seen in patients and significantly impair daily functioning, but their exact biological causes are still unclear.
- A study with 1,837 adults hospitalized due to COVID-19 identified two specific biomarker profiles from their blood tests that can predict cognitive issues 6 to 12 months post-infection.
- The first profile involves high fibrinogen levels linked to cognitive impairments, while the second profile, marked by elevated D-dimer levels, connects more with subjective cognitive issues and work performance, with fatigue and shortness of breath playing a mediating role.