Publications by authors named "P Manoj"
Article Synopsis
- - The study focuses on synthesizing a series of 4,6-diarylpyrimidin-2-amine derivatives that exhibit adjustable optical properties depending on the aryl groups attached to them, both in solid and solution states.
- - The synthesized compounds showed significant variability in their optical characteristics, including absorption and emission rates, with quantum yields ranging from 8.11% to 71.00% in DMF and specific fluorescence lifetimes.
- - The results suggest that these derivatives have potential applications in optoelectronics due to their unique dual-state emission properties and the ability to modify energy levels through different substituents.
This study aimed to investigate the potential protective effects of riociguat, a soluble guanylyl cyclase (sGC) stimulator, on kidney function and structure in rats with acute kidney injury (AKI) induced by the chemotherapeutic drug doxorubicin (DX). Rats were subjected to a single intraperitoneal injection of DX (13.5 mg/kg) on the 5th day, either alone or in combination with low-dose riociguat (3 mg/kg/day), or high-dose riociguat (10 mg/kg/day) for 8 consecutive days.
View Article and Find Full Text PDFObjectives: The purpose of this study was to assess, in a tertiary care context, the significance of C-reactive protein (CRP) in salivary gland illness.
Methods: This prospective research included 100 consecutive individuals with symptoms indicative of illness of the salivary glands. Demographic information, clinical information, and presenting symptoms were noted.
Article Synopsis
- Patients with small-cell lung cancer (SCLC) usually have a hard time and don't get great results from current treatments.
- A new study shows that blocking a protein called ATR can help destroy cancer cells and improve the immune system's response against tumors.
- When ATR is blocked along with another treatment called PD-L1, it works better than PD-L1 alone, offering hope for new ways to help people with SCLC.