Publications by authors named "P Manimaran"

Metol (MTO), a commonly used photographic developer, has become an environmental pollutant due to its extensive use and subsequent release into water sources. The accumulation of MTO poses significant risks, including aquatic toxicity and potential bioaccumulation, leading to adverse effects on ecosystems. To address these environmental challenges, we developed a La₂NiO combined with graphene oxide (La₂NiO₄@GO) nanocomposite modified glassy carbon electrode (GCE) for the ultrasensitive detection of MTO.

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Article Synopsis
  • Cervical cancer remains a major global health threat, being the fourth leading cause of cancer-related deaths in women, with over 604,000 cases reported in 2020.
  • Recent advancements in technology have allowed researchers to identify and propose several candidate genes that could aid in developing new therapeutic strategies for cervical cancer.
  • The study employed a novel analytical approach involving cross-correlations to prioritize key candidate genes and identified six genes (CDH2, PAIP1, BRAF, EPB41L3, OSMR, and RUNX1) as significant for tumor progression, emphasizing their potential for further experimental validation in cervical cancer research.
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Context: Splenic B-cell lymphoma/leukemia with prominent nucleoli (SBLPN) aka hairy cell leukemia variant (HCL-v) is a rare B-cell chronic lymphoproliferative disorder. The main diagnostic challenge is to differentiate SBLPN from Classical hairy cell leukemia (HCL-c), as the former faces inferior responses to therapies and a poor prognosis.

Aims: The aim is to discuss the clinic-hematological and immunophenotyping findings of three cases of SBLPN.

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Poornima Manimaran  Plasma cell leukemia (PCL) is very uncommon and aggressive neoplasm constituting 2 to 4% of all plasma cell dyscrasias. By definition, clonal plasma cells should make up 20% of peripheral blood or have an absolute plasma cell count of 2 × 10 cells/cu.mm.

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