Publications by authors named "P Mangoni"
Article Synopsis
- - The study surveyed 2,751 parents, elderly individuals, and health care workers in the DRC to assess their knowledge, attitudes, and practices regarding both routine and outbreak-related vaccinations.
- - While overall acceptance for routine vaccinations was high (90%), only 57% accepted outbreak vaccinations, with parents and the elderly expressing more concerns about side effects and feeling less informed.
- - Health care workers showed the highest acceptance of vaccines and could significantly enhance vaccination rates, especially during outbreaks, if the vaccine supply chain operates effectively.
Article Synopsis
- Honey bee colonies are likely to experience co-exposure to pesticides and viruses, particularly thiamethoxam and Chronic bee paralysis virus (CBPV), which can affect their health and survival.
- A study found that while co-exposure didn't significantly affect bee survival or their ability to break down thiamethoxam, it did increase CBPV loads to levels typically seen in severe infections.
- The impact of this co-exposure may vary with the season, as bees in spring and summer are more commonly exposed and have different physiological responses than the winter bees studied.
Pathogens and pesticides are likely to co-occur in honeybee hives, but much remains to be investigated regarding their potential interactions. Here, we first investigated the metabolisation kinetics of thiamethoxam in chronically fed honeybees. We show that thiamethoxam, at a dose of 0.
View Article and Find Full Text PDFBackground: In Human African Trypanosomiasis, neurological symptoms dominate and cardiac involvement has been suggested. Because of increasing resistance to the available drugs for HAT, new compounds are desperately needed. Evaluation of cardiotoxicity is one parameter of drug safety, but without knowledge of the baseline heart involvement in HAT, cardiologic findings and drug-induced alterations will be difficult to interpret.
View Article and Find Full Text PDFObjectives: To estimate the frequency and evolution of heart involvement in human African trypanosomiasis (HAT) using electrocardiogram (ECG) findings; to describe these findings and to assess the frequency and clinical relevance of symptoms and signs before and after treatment.
Methods: In a prospective cohort study ECG findings, signs and symptoms consistent with heart failure and cardiac laboratory parameters were studied at baseline, 2 days after the end of treatment and 3 months later.
Results: Major ECG alterations were significantly more frequent in HAT patients than in healthy controls (71%vs.