Management of ectopia lentis in children.

The medical management of ectopia lentis involves refractive correction as well as co-management of any associated systemic disease. Surgical management remains a challenge, as inherent defects in the lens capsule make implantation of an intraocular lens (IOL) difficult. Multiple visual rehabilitative measures are available such as aphakic contact lenses or spectacles, capsular bag fixation with implantation of in-the-bag IOL, iris-fixated, and scleral-fixated IOL.

Simple limbal epithelial transplantation versus cultivated limbal epithelial transplantation in ocular burns.

Purpose: To compare the outcomes of simple limbal epithelial transplantation (SLET) with cultivated limbal epithelial transplantation (CLET) for the management of total limbal stem cell deficiency (LSCD) in eyes with unilateral ocular burns.

Design: Randomized controlled trial.

Methods: 100 patients (100 eyes) with unilateral total LSCD following ocular burns undergoing autologous Limbal Stem Cell Transplantation (LSCT) were enrolled and randomized into SLET and CLET groups.

Copper-catalyzed (4+3)-cycloaddition of 4-indolylcarbinols with aziridines: stereoselective synthesis of azepinoindoles.

Copper(I)-catalyzed (4+3)-cycloaddition of 4-indolylcarbinols with aziridines has been accomplished to furnish azepinoindoles. The chirality transfer, substrate scope, functional group tolerance, natural product modification and tandem C-C/C-N bond formation are the important practical features.

Comparative Evaluation of Topical Monotherapy (Natamycin or Natasol) and Combination Therapy (Natamycin and Voriconazole) in Mild-Moderate Fungal Keratitis.

Purpose: To compare the efficacy of monotherapy (natamycin 5% or Natasol 1%) versus combination therapy (natamycin 5% and voriconazole 1%) in the treatment of mild-moderate fungal keratitis.

Methods: In a prospective, comparative, interventional study, 60 eyes of 60 patients with mild-moderate fungal keratitis were included and randomized in 3 groups based on the topical antifungal therapy received: group 1, natamycin 5%; group 2, Natasol 1% (1% w/v aqueous natamycin); and group 3, combination of natamycin 5% and voriconazole 1%.

Results: 51 of 60 cases (85%) resolved with medical management only.

Visual outcomes with implantable Collamer lens versus small incision lenticule extraction in moderate-high myopia: A pilot study.

Purpose: To compare the visual outcomes of implantable Collamer lens (ICL) with small incision lenticule extraction (SMILE) in cases of moderate-high myopia.

Methods: A prospective comparative study was conducted on 60 eyes of 30 patients with moderate-high myopia (-3D to -8D with astigmatism ≤1 D) at a tertiary eye care center. Patients underwent either SMILE or ICL in both eyes and had a postoperative follow-up of 1 year.