Publications by authors named "P Magistri"

Liver transplantation (LT) is a curative strategy for hepatocellular carcinoma (HCC), but the risk of HCC recurrence remains a challenging problem. In patients with HCC recurrence after LT (HCC-R_LT), the locoregional and surgical approaches are complex, and the guidelines do not report evidence-based strategies for the management of immunosuppression. In recent years, immunotherapy has become an effective option for patients with advanced HCC in pre-transplant settings.

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Minimally invasive liver surgery has become widely accepted as a safe and effective approach, especially with experienced surgeons. Robotic hepatectomy may offer significant benefits in challenging procedures like caudate lobe resection. The caudate lobe's intricate anatomy and deep-seated location make its resection particularly challenging, with limited reports on minimally invasive techniques.

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Situs viscerum inversus totalis (SIT) is a rare congenital anomaly. Deceased donors with this condition are often declined because of the technical issues in both the organ's procurement and its transplant. Only eight cases of deceased donor organs with SIT were reported to be used for liver transplantation (LT).

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Article Synopsis
  • The study analyzed the relationship between the neoangiogenic transcriptomic signature (nTS) and various clinical outcomes in patients with hepatocellular carcinoma (HCC), involving a large cohort of 584 patients.
  • Findings showed that nTS is linked to more aggressive disease characteristics, limited treatment options, and poorer overall survival compared to those without nTS, with significant consequences on treatment effectiveness and patient prognosis.
  • Repeated transarterial chemoembolization (TACE) was found to convert some patients from nTS- to nTS+, which correlated with worsened survival rates and changes in microRNA patterns, emphasizing the nTS's role in managing and predicting HCC outcomes.
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