Publications by authors named "P Machi"
Background: There are limited therapeutic options in cases of failed reperfusion (modified thrombolysis in cerebral infarction [mTICI] score < 2b) after stent-retriever and/or aspiration based endovascular treatment (EVT) for acute ischemic stroke. Despite the absence of data supporting its use, rescue therapy (balloon angioplasty and/or stent implantation) is often utilized in such cases. Studies are limited to large vessel occlusions, while the outcomes and complications after rescue therapy in medium/distal vessel occlusions (MDVOs) have not been reported.
View Article and Find Full Text PDFBackground And Purpose: Thrombectomy in distal, medium vessels is a topic of increasing interest. To date, there are few studies focused on performance of ≤5F catheters in medium vessels. The purpose of this study is to compare the performance of the 3F, 4F, and 5F MIVI Neuroscience Q Catheters versus Penumbra 3F, 4F, and MicroVention Sofia 5F Catheters.
View Article and Find Full Text PDFBackground: Virtual simulation is increasingly used for aneurysm treatment. This study aimed to explore whether mechanical behavior biomarkers of the Woven EndoBridge (WEB) device as computed by Sim&Size simulation software were associated with aneurysmal occlusion status at follow-up.
Methods: Consecutive patients with aneurysms treated with WEB were retrospectively enrolled (January 2014 to December 2021).
Article Synopsis
- The study investigates the use of contrast-enhanced cone beam CT (CE-CBCT) for better visualization of the distal part of clots during mechanical thrombectomy (MT) for ischemic strokes, as conventional imaging methods face challenges in this regard.!* -
- Results showed that CE-CBCT significantly outperformed traditional imaging techniques like 3D rotational angiography (3DRA) and digital subtraction angiography (DSA) in visualizing the distal edges of clots and the arteries beyond the blockage.!* -
- Enhanced visualization with CE-CBCT correlated with improved MT effectiveness, demonstrated by higher rates of successful clot removal and better collateral blood flow, indicating its potential value in stroke treatment.!*
Article Synopsis
- * Data from 459 patients with vessel perforation showed a 90-day mortality rate of 51.9%, with only 16.3% achieving a favorable recovery (mRS 0-2).
- * The findings indicate that large vessel perforation leads to worse outcomes, while thrombolysis doesn’t worsen prognoses; quick management of bleeding is crucial for survival.