Publications by authors named "P MacLeod"

Background: Through medicare, residents in Canada are entitled to medically necessary physician services without paying out of pocket, but still many people struggle to access primary care. We conducted a survey to explore people's experience with and priorities for primary care.

Methods: We conducted an online, bilingual survey of adults in Canada in fall 2022.

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Article Synopsis
  • SETD1A is a gene that encodes a histone methyltransferase linked to cell cycle regulation and has been associated with neurodevelopmental disorders like intellectual disability and schizophrenia.
  • This study systematically reviews existing literature and presents new case reports to better understand the psychiatric symptoms and neurodevelopmental features of individuals with SETD1A variants related to schizophrenia.
  • Findings suggest that while people with SETD1A-linked schizophrenia share some traits, there’s significant variability in their symptoms, and recognizing these variants could be important for future personalized treatment options in mental health care.
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Purpose: The human papillomavirus (HPV) is well recognised as a factor in developing oropharyngeal cancer (OPC). A booklet for HPV-OPC patients aimed to deliver evidence-based messages in everyday language, in a way to minimise negative psychological impacts on patients. Our study explored the suitability of the booklet for use.

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Investigating whether changes within fish populations may result from harvesting requires a comprehensive approach, especially in more data-sparse northern regions. Our study took a three-pronged approach to investigate walleye population change by combining Indigenous knowledge (IK), phenotypic traits, and genomics. We thank Larson et al.

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Phospholipase A2G6-associated neurodegeneration (PLAN) is a rare early-onset monogenic neurodegenerative movement disorder which targets the basal ganglia and other regions in the central and peripheral nervous system; presenting as a series of heterogenous subtypes in patients. We describe here a B6.C3-Pla2g6 mouse model of PLAN which presents with early-onset neurodegeneration at 90 days which is analogous of the disease progression that is observed in PLAN patients.

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