"Tobacco Free With FDNY": the New York City Fire Department World Trade Center Tobacco Cessation Study.

Context: After the World Trade Center (WTC) collapse, 15% (1,767) of rescue workers from the Fire Department of the City of New York (FDNY) considered themselves to be current cigarette smokers. Post-WTC collapse, 98% reported acute respiratory symptoms, and 81% reported health concerns. Nonetheless, 29% of current smokers increased tobacco use, and 23% of ex-smokers resumed cigarette smoking.

PRODISTIN Web Site: a tool for the functional classification of proteins from interaction networks.

Unlabelled: The PRODISTIN Web Site is a web service allowing users to functionally classify genes/proteins from any type of interaction network. The resulting computation provides a classification tree in which (1) genes/proteins are clustered according to the identity of their interaction partners and (2) functional classes are delineated in the tree using the Biological Process Gene Ontology annotations.

Availability: The PRODISTIN Web Site is freely accessible at http://gin.

GOToolBox: functional analysis of gene datasets based on Gene Ontology.

We have developed methods and tools based on the Gene Ontology (GO) resource allowing the identification of statistically over- or under-represented terms in a gene dataset; the clustering of functionally related genes within a set; and the retrieval of genes sharing annotations with a query gene. GO annotations can also be constrained to a slim hierarchy or a given level of the ontology. The source codes are available upon request, and distributed under the GPL license.

[Effect of acute administration of antidepressive agents at 2 P.M. on plasma and pineal levels of melatonin in the rat].

The authors measured the effect of different antidepressant drugs on the pineal production of melatonin in order to see if this test can be used in an antidepressants screening protocol. Six antidepressant drugs belonging to different pharmacologic classes have been tested. The results show that all the molecules used enhance the plasmatic and pineal concentration of melatonin.

[Parkinson's disease and mental deterioration. Apropos of 30 cases].

The influence of Parkinson illness on intellectual faculties is appreciated in different ways. The existence of a real parkinson dementia is contested by some who see in the intellectual impoverishment of these patients a simple decline in efficiency. This is often partial and linked to neurological consequences which are not always taken into account by psychometric tests.