Publications by authors named "P M Yates"
Background: Cerebral microbleeds (CMBs) are small brain haemorrhages, identified by magnetic resonance imaging (MRI). They indicate potential for cognitive decline and mortality in memory clinic attendees. The presence of more than four CMBs is exclusionary for some clinical trials of disease-modifying therapies for Alzheimer's disease (AD).
View Article and Find Full Text PDFIntroduction: Micromotion analysis predicts component fixation survival in Total Knee Arthroplasty (TKA) but a paucity of literature exists for medial pivot designs. This clinical study examined the tibial component micromotion in a second-generation medial pivot TKA.
Methods: This prospective single-center clinical cohort trial involved 35 patients with a mean patient age of 71 years.
Kinetoplastid parasites cause diseases that threaten human and animal health. To survive transitions between vertebrate hosts and insect vectors, these parasites rely on precise regulation of gene expression to adapt to environmental changes. Since gene regulation in Kinetoplastids is primarily post-transcriptional, developing efficient genetic tools for modifying genes at their endogenous loci while preserving regulatory mRNA elements is crucial for studying their complex biology.
View Article and Find Full Text PDFArticle Synopsis
- Supporting clinical teams to enhance care for palliative patients and their caregivers is a top priority, and patient-reported experience measures (PREMs) like consideRATE can help identify areas for improvement.
- A study in an Australian hospital showed a 71% response rate from eligible patients and their caregivers, with a majority preferring to complete the measure electronically, and many needing assistance.
- The findings suggest that using consideRATE is feasible and provides valuable feedback to clinicians, who noted the importance of having accessible and context-sensitive data for quality improvement.
Article Synopsis
- Home-based palliative and supportive care for heart failure patients enhances quality of life and reduces healthcare costs while benefiting caregivers.
- This study aims to identify and describe the essential components of such care, using a scoping review methodology.
- Key findings indicate that a multidisciplinary team, led by nurses, is crucial for effective symptom management, education, and advance care planning in this context, which points to a need for future research on digital interventions and team composition.