Publications by authors named "P M Wu"

Abundant polyphenols in Flos Sophorae Immaturus tea (FSIt) exhibited xanthine oxidase (XO) inhibitory activity. However, the XO inhibitory activity of FSIt was closely related to the processing methods. Herein, organic acids were employed as catalysts for polyphenol conversion during heat treatment and applied to enhance the XO inhibitory activity of FSIt; the potential mechanisms were clarified by polyphenols degradation and conversion analysis, omission experiment, and interaction assay.

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Marine zooplankton communities represent one of the most diverse and abundant species groups on earth. To investigate the ecological niche characteristics and interspecific interactions of marine zooplankton, and to elucidate their role in carbon deposition and biogeochemical cycling, we conducted a study on the zooplankton community near Taishan in the South China Sea between December 2015 and September 2016. Using niche breadth, niche overlap, the variance ratio method, chi-square tests, and linkage coefficients, we analyzed the interrelationships among the major zooplankton species.

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Returning raw straw to the soil can significantly elevate soil methylmercury (MeHg) and crop mercury (Hg) levels, underscoring the need to investigate safer approaches to straw utilization in mercury-contaminated regions. In this study, rice straw underwent anaerobic fermentation with the addition of sulfate, and the resulting fermentation products were utilized in a pot experiment involving water spinach to assess the impact of anaerobically fermented straw return on soil Hg methylation and its bioaccumulation. Findings revealed that the addition of sulfate during straw fermentation markedly increased the fermentation degree of the products, and sulfate was converted into organic sulfur-containing ligands that can functionalize the fermentation residuals.

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Thermoacidophilic archaea thrive in environments with high temperatures and low pH where cells are prone to severe oxidative stress due to elevated levels of reactive oxygen species (ROS). While the oxidative stress responses have been extensively studied in bacteria and eukaryotes, the mechanisms in archaea remain largely unexplored. Here, using a multidisciplinary approach, we reveal that SisPerR, the homolog of bacterial PerR in Saccharolobus islandicus REY15A, is responsible for ROS response of transcriptional regulation.

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Rheumatoid arthritis (RA) is a kind of inflammation homeostasis disorder that dysfunctions the joints. Clinically, medications against RA focus simply on mitigating the focal inflammation, without considering pro-osteogenesis re-modeling of the bone microenvironment. In the present work, 2D layered calcium disilicide nanoparticles (CSNs) are fabricated by facile aqueous exfoliation.

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Synopsis of recent research by authors named "P M Wu"

  • - P M Wu's recent research emphasizes the need for innovative translational and clinical research in China to address the unique cancer landscape, highlighting the disparities in cancer care and the challenges faced by local pharmaceutical companies due to the country's specific disease burdens.
  • - The author has contributed to veterinary science by investigating the genetic factors related to piglet diarrhea through a genome-wide association study, aiming to identify key regulatory genes to improve health in livestock.
  • - Wu's work in prenatal diagnostics includes several case reports utilizing chromosome microarray analysis to uncover genetic anomalies in fetuses, thereby advancing understanding and early diagnosis of congenital disorders such as Jacobsen syndrome and chromosome 5q interstitial deletion syndrome.