Regenerative failure of sympathetic axons contributes to deficits in functional recovery after nerve injury.

Renewed scientific interest in sympathetic modulation of muscle and neuromuscular junctions has spurred a flurry of new discoveries with major implications for motor diseases. However, the role sympathetic axons play in the persistent dysfunction that occurs after nerve injuries remains to be explored. Peripheral nerve injuries are common and lead to motor, sensory, and autonomic deficits that result in lifelong disabilities.

Informed choices for some, but not for others: An exploration of Australian midlife women's participation in mammography screening by social class.

Background: Population-level mammography screening for early detection of breast cancer is a secondary prevention measure well-embedded in developed countries, and the implications for women's health are widely researched. From a public health perspective, efforts have focused on why mammography screening rates remain below the 70% screening rate required for effective population-level screening. From a sociological perspective, debates centre on whether 'informed choice' regarding screening exists for all women and the overemphasis on screening benefits, at the cost of not highlighting the potential harms.

Prevention of type 2 diabetes mellitus among people with Middle Eastern backgrounds living in high-income countries: a systematic review.

Objectives: This systematic review aims to assess the available evidence on the prevention of type 2 diabetes mellitus (T2DM) among Middle Eastern (ME) populations residing in high-income countries (HICs). The review focuses on two key aspects: (1) evaluating the efficacy of interventions for improving health outcomes and (2) examining the barriers to and facilitators of the implementation and effectiveness of interventions.

Design: Systematic review.

Phase 2 Open-Label Trial of Brentuximab Vedotin with Pembrolizumab in PD-1 Pretreated Metastatic Non-Small Cell Lung Cancer and Metastatic Cutaneous Melanoma.

Purpose: Brentuximab vedotin (BV) is hypothesized to selectively deplete T regulatory cells (Tregs) that express CD30 and re-sensitize tumors to anti-(PD-1) therapy. This study evaluated responses to BV+pembrolizumab post PD-1 and explored corresponding biomarkers.

Methods: 55 patients with metastatic non-small cell lung cancer (NSCLC) and 58 with metastatic cutaneous melanoma received ≥1 dose of BV+pembrolizumab.

Correction: Physical activity and sedentary behavior levels among individuals with mental illness: A cross-sectional study from 23 countries.

[This corrects the article DOI: 10.1371/journal.pone.