The development of materials toward ppb-level nitric oxide (NO) sensing at room temperature remains in high demand for the monitoring of respiratory inflammatory diseases. In order to find an iron-containing molecule without steric hindrance to combine with graphene for room temperature NO gas sensing, here a supramolecular assembly of ferrocene (Fc) and reduced graphene oxide (rGO) was designed and prepared for NO sensing. The assembly of Fc/rGO was characterized using FT-IR, TEM, and XPS measurements.
View Article and Find Full Text PDFBackground: Early intervention in psychosis (EIP) services improve outcomes for young people, but approximately 30% disengage.
Aims: To test whether a new motivational engagement intervention would prolong engagement and whether it was cost-effective.
Method: We conducted a multicentre, single-blind, parallel-group, cluster randomised controlled trial involving 20 EIP teams at five UK National Health Service (NHS) sites.
Introduction: Inequity in access to healthcare in the United Kingdom can have a profound impact on people's ability to manage their health problems. Link work interventions attempt to overcome the socioeconomic and structural barriers that perpetuate health inequalities. Link workers are typically staff members without professional clinical qualifications who support patients to bridge the gap between services.
View Article and Find Full Text PDFThe standard of care for adult patients with gliomas, glioneuronal and neuronal tumors consists of combinations of surgery, radiotherapy, and chemotherapy. For many systemic cancers, targeted treatments are a major part of the standard treatment, however, the predictive significance of most of the targets for treatment in systemic cancer are less well established in central nervous system (CNS) tumors . In 2023 the EANO Guideline Committee presented evidence based recommendations for rational testing of molecular targets for targeted treatments.
View Article and Find Full Text PDFBr J Psychiatry
December 2024
Background: Understanding inequalities in outcomes between demographic groups is a necessary step in addressing them in clinical care. Inequalities in treatment uptake between demographic groups may explain disparities in outcomes in people with first-episode psychosis (FEP).
Aims: To investigate disparities between broad demographic groups in symptomatic improvement in patients with FEP and their relationship to treatment uptake.