Publications by authors named "P M Strappe"

Correction for 'Attenuation of metabolic syndrome in the ob/ob mouse model by resistant starch intervention is dose dependent' by Anqi Wang , , 2019, , 7940-7951, https://doi.org/10.1039/C9FO01771B.

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The COVID-19 pandemic has had a significant and lasting impact on the world. Four years on, despite the existence of effective vaccines, the continuous emergence of new SARS-CoV-2 variants remains a challenge for long-term immunity. Additionally, there remain few purpose-built antivirals to protect individuals at risk of severe disease in the event of future coronavirus outbreaks.

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Three mannan polysaccharides and their oligosaccharides were investigated in terms of physicochemical characteristics and effects on gut microbiota. Oligosaccharides from guar gum had the fastest fermentation kinetics for SCFAs generation at the initial stage, while the locust bean of both polymers and oligosaccharides demonstrated the lowest SCFAs through the whole fermentation process. In contrast, konjac gum steadily increased SCFAs and reached its maximum level at 24 h fermentation, indicating its fermentation character may be associated with its rheological properties.

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An animal model of Cd-induced kidney damage was designed to investigate the nephroprotective potential of the probiotic-fermented (FGL) metabonomic analysis. The results showed that FGL enhanced sugar and amino acid metabolism. The interaction of (GL) and probiotics efficiently elevated short-chain fatty acid production following gut microbiota fermentation.

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Background: Ageing and associated cognitive impairments are becoming serious issues around the world. In this study, the physiological properties of three kinds of complexes of fatty acid (capric, stearic and oleic acid, respectively) and de-branched starch molecules were investigated via a d-galactose-induced ageing model. This study revealed differences in the regulation of cognitive impairment and brain damage following intervention of different complexes, which might highlight a potent approach for the prevention of this chronic disease.

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