Publications by authors named "P M Queiroz"
Article Synopsis
- The diagnosis of retroviruses is crucial for controlling pandemics, but current methods like RT-qPCR are costly and logistically challenging.
- A novel detection method for SARS-CoV-2 viral RNA was developed, combining ribozymes and FRET-based DNA hairpins for enhanced sensitivity.
- The results showed that this new approach cleaved viral RNA quickly and effectively, allowing for specific detection and the potential for adaptation to other viruses while also exploring low-cost detection options.
Background: Approaches to documenting the software patterns of a system can support intentionally and manually documenting them or automatically extracting them from the source code. Some of the approaches that we review do not maintain proximity between code and documentation. Others do not update the documentation after the code is changed.
View Article and Find Full Text PDFTriple-negative breast cancer (TNBC) exhibits a proclivity for early recurrence and development of metastasis. Moreover, drug resistance tends to arise few months following chemotherapeutic regimen with agents such as Doxorubicin, Paclitaxel, Docetaxel, and Cisplatin. miR-200 family and miR-205 are considered key regulators of metastasis by regulating the Epithelial-to-mesenchymal transition (EMT) via inhibiting ZEB1.
View Article and Find Full Text PDFArticle Synopsis
- Polymyxin B (PMB) is currently one of the few options to treat serious infections caused by drug-resistant Gram-negative bacteria, but resistance to PMB is emerging.
- This study tests several chemical compounds, including 3,5-dinitrobenzoic acid derivatives and isoniazid-acylhydrazones, to see if they can enhance the effectiveness of PMB against resistant bacteria.
- Results showed that DNH derivatives significantly improved PMB's activity against 80% of tested strains, allowing for effective treatment at much lower concentrations than PMB alone, suggesting they could be valuable in fighting resistant infections.
Objective: to understand the bioethical perspectives on mobile tracking device use.
Methods: theoretical study based on action research, carried out with eight graduate students from a public university. A focus group was used, with a thematic content analysis methodology with a codebook structure, approved by the Research Ethics Committee.