[Education, can it be done differently? A sketch of a new training structure for medical specialists].

A working group of the 'Resident Education 2025' project of the Association Medical Specialists has the task of developing a training structure for future medical specialist, which is more in line with the desired interprofessional collaboration within a network, with the right care on the right place. Responding to the required flexibility and deployment of medical specialists, also outside the intramural environment. In doing so, we want to safeguard and strengthen the enthusiasm of future and current specialists, among other things through a better work-life balance.

SARS-CoV-2-Induced Multisystem Inflammatory Syndrome in a Young Adult: Case Report.

We describe a case of a previous healthy 20-year-old male athlete who presented with an atypical clinical profile with multiorgan involvement within five weeks after confirmed SARS-CoV-2 infection, suggestive for multisystem inflammatory syndrome (MIS); MIS is a rare, potentially life-threatening complication associated with SARS-CoV-2. MIS shares similar clinical features compatible with several overlapping lifethreatening hyperinflammatory syndromes, such as incomplete Kawasaki Disease (KD) and toxic shock syndrome (TSS) associated to a cytokine storm suggestive of a macrophage activation syndrome (MAS) without fulfilling the criteria for hemophagocytic lymphohistiocytosis (HLH), that may create a great challenge to distinguish between them. MIS should promptly be considered and treated, as uncontrolled MIS has a high mortality.

[Use of quality assessments by internists: added pressure to carry out assessments or an aid to improve quality?].

Objective: To obtain an insight into how internists and residents use quality assessments and their opinions on these assessments.

Design: Questionnaire survey.

Method: All 139 internists and residents who attended a national training day on internal medicine in 2012 were invited to answer questions anonymously on the actual use of various quality assessments and to give their opinion on these assessments.

Diabetes-related distress, insulin dose, and age contribute to insulin-associated weight gain in patients with type 2 diabetes: results of a prospective study.

Objective: The determinants of insulin-associated weight gain in type 2 diabetes mellitus (T2DM) are partly unknown. Therefore, we conducted a prospective study to identify predictors of insulin-associated weight gain.

Research Design And Methods: In patients with T2DM, we assessed physical activity by accelerometry and measured diabetes-related distress by questionnaires before and 6 and 12 months after starting insulin therapy.

Correlations between peripheral blood Coxiella burnetii DNA load, interleukin-6 levels, and C-reactive protein levels in patients with acute Q fever.

From 2007 to 2010, the Netherlands experienced the largest reported Q fever outbreak, with >4,000 notified cases. We showed previously that C-reactive protein is the only traditional infection marker reflecting disease activity in acute Q fever. Interleukin-6 is the principal inducer of C-reactive protein.