Hereditary spherocytosis presenting as indolent leg ulcers.

Indolent leg ulcertation, which is the rarest manifestation of hereditary spherocytosis, started at the age of 5 years affecting a 15-year-old boy and his mother is reported. Review of literature showed very few reports from India and abroad. The response to oral folic acid was excellent.

Hypopigmented macules in leprosy--a histopathological and histochemical study of melanocytes.

Study of the number of melanocytes and amount of pigmentation in hypopigmented lesions and adjacent normal areas in 20 leprosy patients showed no differences in these parameters. It appears that hypopigmentation in leprosy lesions could be caused by defective transfer of melanin into keratinocytes.