Effect of Tiered Implementation of Clinical Decision Support System for Acute Kidney Injury and Nephrotoxin Exposure in Cardiac Surgery Patients.

Background:  Nephrotoxin exposure may worsen kidney injury and impair kidney recovery if continued in patients with acute kidney injury (AKI).

Objectives:  This study aimed to determine if tiered implementation of a clinical decision support system (CDSS) would reduce nephrotoxin use in cardiac surgery patients with AKI.

Methods:  We assessed patients admitted to the cardiac surgery intensive care unit at a tertiary care center from January 2020 to December 2021, and August 2022 to September 2023.

MMORF-FSL's MultiMOdal Registration Framework.

We present MMORF-FSL's MultiMOdal Registration Framework-a newly released nonlinear image registration tool designed primarily for application to magnetic resonance imaging (MRI) images of the brain. MMORF is capable of simultaneously optimising both displacement and rotational transformations within a single registration framework by leveraging rich information from multiple scalar and tensor modalities. The regularisation employed in MMORF promotes local rigidity in the deformation, and we have previously demonstrated how this effectively controls both shape and size distortion, leading to more biologically plausible warps.

Comparative Analysis of Force-Sensitive Resistors and Triaxial Accelerometers for Sitting Posture Classification.

Sedentary behaviors, including poor postures, are significantly detrimental to health, particularly for individuals losing motion ability. This study presents a posture detection system utilizing four force-sensitive resistors (FSRs) and two triaxial accelerometers selected after rigorous assessment for consistency and linearity. We compared various machine learning algorithms based on classification accuracy and computational efficiency.

Regulation of the Promoter for Capsular Polysaccharide Synthesis in Serogroup B by HTH_XRE Family Transcription Factor.

Unlabelled: The capsular polysaccharide synthesis ( ) locus of is implicated in invasive meningococcal disease. The synthesis ( ) and transport ( ) operons are transcribed in opposite directions from a common intergenic region and expression is negatively regulated by the bacterial two-component system and thermosensitive RNA folding. However, these mechanisms do not fully explain the stationary phase responses and the cis-acting elements remain to be fully characterized.