Publications by authors named "P M Gocze"
Endometrial cancer is the most common invasive gynecologic malignancy in developed countries. The best survival rates are expected after surgical removal, thus the aim of a complex treatment is to achieve resecability in locally and locoregionally advanced disease. The primary purpose of this study was to evaluate if the neoadjuvant systemic treatment leads to better overall survival compared to irradiation solely.
View Article and Find Full Text PDFIntroduction And Aim: The aim of our study was to evaluate the prognostic factors and treatment options of a very rare and highly aggressive type of uterine neoplasms, the malignant mixed Müllerian tumor, known as carcinosarcoma.
Method: Between 2009 and 2017, 29 patients were treated with malignant mixed Müllerian tumor. At stage I, surgery and postoperative radiotherapy were performed.
Article Synopsis
- Granulosa cell tumor of the ovary is the most common type of sex cord stromal tumor, accounting for 2-5% of ovarian cancers, and can be malignant and hormonally active, with recurrences often occurring after 5 years.
- The study presents two cases of postmenopausal women with adult-type granulosa cell tumors: one with a recurrent tumor and one without, highlighting the monitoring of their urinary steroid profiles over several years.
- The findings suggest that increased urinary steroid levels can correlate with tumor recurrence, indicating that urinary steroid profiling may be a better follow-up method over traditional serum hormone measurements and conventional tumor markers.
Background: Treatment possibilities of metastatic renal cell carcinoma (mRCC) have recently changed dramatically prolonging the overall survival of the patients. This kind of development brings new challenges for the care of mRCC.
Case Presentation: A 22 year-old female patient with translocation type mRCC, who previously had been treated for nearly 5 years, became pregnant during the treatment break period.
Background/aim: The role of oncogenic or high-risk human papillomavirus (HPV) in cervical carcinogenesis is inevitable, yet not fully understood. Detailed analysis of microRNA (miRNA) alterations occurring during high-risk HPV transformation will increase our current understanding over cervical carcinogenesis. The two main aims of the study were: (i) finding association between HPV infection characteristics and socio-demographic variables, (ii) finding an predictors of clinical outcome.
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