Visualizing the WHO "My Five Moments for Hand Hygiene," Framework: A Virtual Reality Training Program for Improving Hand Hygiene Adherence Among Nurses.

Background: Healthcare-associated infections (HAIs) contribute to patient morbidity and mortality. Hand hygiene is essential for preventing HAIs, but training can fail to transfer to clinical practice. Experiential learning through virtual reality (VR) may improve adherence by offering realistic practice opportunities and feedback.

Iron-sulfur cluster-dependent enzymes and molybdenum-dependent reductases in the anaerobic metabolism of human gut microbes.

Metalloenzymes play central roles in the anaerobic metabolism of human gut microbes. They facilitate redox and radical-based chemistry that enables microbial degradation and modification of various endogenous, dietary, and xenobiotic nutrients in the anoxic gut environment. In this review, we highlight major families of iron-sulfur (Fe-S) cluster-dependent enzymes and molybdenum cofactor-containing enzymes used by human gut microbes.

Leveraging ordered voids in microporous perovskites for intercalation and post-synthetic modification.

We report the use of porous organic layers in two-dimensional hybrid organic-inorganic perovskites (HOIPs) to facilitate permanent small molecule intercalation and new post-synthetic modifications. While HOIPs are well-studied for a variety of optoelectronic applications, the ability to manipulate their structure after synthesis is another handle for control of physical properties and could even enable use in future applications. If designed properly, a porous interlayer could facilitate these post-synthetic transformations.

Exploring the influence of H-bonding and ligand constraints on thiolate ligated non-heme iron mediated dioxygen activation.

Converting triplet dioxygen into a powerful oxidant is fundamentally important to life. The study reported herein quantitatively examines the formation of a well-characterized, reactive, O-derived thiolate ligated Fe-superoxo using low-temperature stopped-flow kinetics. Comparison of the kinetic barriers to the formation of this species two routes, involving either the addition of (a) O to [Fe(S N(Pr,Pr))] (1) or (b) superoxide to [Fe(S N(Pr,Pr))] (3) is shown to provide insight into the mechanism of O activation.

Data discrepancies: Italian ministry reports on abortion, contextualised.

The Italian Ministry of Health reports annually on activities related to abortion and fertility, providing quantitative data that looks ripe for analysis. Actors ranging from activists to medical providers to European courts have criticised the data as misleading, but the Ministry reports have not changed. In this piece, we bring together different perspectives on this data from inside and outside academia and offer guidance on how it should-and should not-be used in research.