Molecular and Immunological Properties of a Chimeric Glycosyl Hydrolase 18 Based on Immunoinformatics Approaches: A Design of a New Anti- Vaccine.

Leishmaniasis is a chronic inflammatory zoonotic illness caused by protozoan flagellates belonging to the genus. Current data suggest that over 1 billion people worldwide are susceptible to infection, primarily in tropical and subtropical countries, where up to 2 million new cases are reported annually. Therefore, the development of a vaccine is crucial to combating this disease.

Evaluation of radiation therapy on grafted and non-grafted defects: an experimental rat model.

Objective: This study aimed to assess the effects of a single-dose radiation therapy (15 Gy) on grafted and non-grafted defects, bone microarchitecture, and collagen maturity.

Methodology: Bone defects were surgically created in rat femurs. The right femur defect was filled with blood clot (group "Clot") and the left femur defect by deproteinized bovine bone mineral graft (group "Xenograft").

Association between non-carious cervical lesions, dentin hypersensitivity and anxiety in young adults: A cross-sectional study.

Objectives: To investigate the prevalence and factors associated with dentin hypersensitivity (DH) and non-carious cervical lesions (NCCLs).

Methods: The analytical cross-sectional study included 157 participants aged between 18 and 45 years, who were clinically examined and answered a questionnaire related to their lifestyle and daily habits (diet, parafunctional habits, temporomandibular disorders, general and oral health) and the Beck Anxiety Inventory. A descriptive analysis of the prevalence of DH and NCCL was performed, both at the individual level and considering the distribution among the teeth.

Patterns of Screen Time From Ages 2 to 6-7 Years in South Brazil: A Prospective Study.

Background: Screen use has become nearly universal, especially in children. Therefore, it is important not only to comprehend its effects on health but also to understand its patterns of use. We aim to describe screen use patterns among children assessed at 2, 4, and 6-7 years, based on device, period of the day, and child/family characteristics.

Green Sol-Gel Synthesis of Iron Oxide Nanoparticles for Magnetic Hyperthermia Applications.

Background/objectives: The unique properties of iron oxide nanoparticles have attracted significant interest within the biomedical community, particularly for magnetic hyperthermia applications. Various synthesis methods have been developed to optimize these nanoparticles.

Methods: In this study, we employed a powdered coconut water (PCW)-assisted sol-gel method to produce magnetite nanoparticles for the first time.