Publications by authors named "P M F Elshout"
Purpose: This study evaluates the feasibility of a comprehensive supervised exercise program (CSEP) for head and neck cancer (HNC) patients during and after (chemo)radiotherapy, integrating quantitative and qualitative data to identify participation barriers and facilitators.
Methods: To investigate the feasibility of the CSEP, a mixed-method study was performed. For the quantitative part, first, adherence to and safety of the CSEP were considered as quantitative feasibility outcome measures.
To determine which flexible ureterorenoscopy program would be most cost-efficient in our center, a cost efficiency analysis and a formula to assess cost efficiency feasibility of a hybrid model were performed. Total cost per case of reusable flexible ureterorenoscopes (rfURS) was retrospectively calculated and compared with two single-use flexible ureterorenoscopes (sufURS) marketed. A mathematical formula was developed from our data to identify the necessary increase of use of rfURS (NIU-rfURS) to be cost-efficient in a hybrid system utilizing sufURS for only high-risk-of-breakage cases.
View Article and Find Full Text PDFThe global demand for biofuels in the transport sector may lead to significant biodiversity impacts via multiple human pressures. Biodiversity assessments of biofuels, however, seldom simultaneously address several impact pathways, which can lead to biased comparisons with fossil fuels. The goal of the present study was to quantify the direct influence of habitat loss, water consumption and greenhouse gas (GHG) emissions on potential global species richness loss due to the current production of first-generation biodiesel from soybean and rapeseed and bioethanol from sugarcane and corn.
View Article and Find Full Text PDFArticle Synopsis
- The management of high-grade renal injuries (Grade IV-V) is debated, with a rise in non-operative management (NOM) but limited comparative outcome data against open surgical exploration.
- A systematic review was conducted analyzing data from various medical databases to assess the safety and effectiveness of NOM compared to open surgery, focusing on mortality rates, renal preservation, hospital stay length, and complications.
- Findings indicated that NOM had significantly better outcomes in terms of overall mortality (0-3% vs 0-29%) and renal preservation (84-100% vs 0-82%), while the complication rates were similar and NOM patients had shorter hospital stays.
Context: The evidence base for optimal acute management of pelvic fracture-related posterior urethral injuries needs to be reviewed because of evolving endoscopic techniques. The current standard of care is suprapubic cystostomy followed by delayed urethroplasty.
Objective: To systematically review the evidence base comparing early endoscopic realignment with cystostomy and delayed urethroplasty regarding stricture rate, the need for subsequent procedures, and functional outcomes.