The harmful effects following the ingestion of mycotoxin-contaminated food include the induction of cancers, mutagenicity, immune suppression, and toxicities that target organs of the digestive, cardiovascular, and central nervous systems. Synthetic fungicides are generally associated with a high toxic residue in food and the development of excessive fungal resistance. This study aimed to determine the antifungal activities against mycotoxigenic fungi of selected South African plant leaves and potentially develop plant-derived bio-fungicides, and, furthermore, to explore the in vitro antioxidant activity and the phytochemical spectra of the compounds of the selected medicinal plant extracts.
View Article and Find Full Text PDFAntifungal and anti-mycotoxigenic activity of 25 acetone leaf extracts of South African medicinal plants with potent antioxidant activity were investigated against three phytopathogenic fungal strains. The extracts exhibited varying degrees of anti-mycotoxigenic effect against , and . (Baker) Sprague exhibited the lowest minimum inhibitory concentration (MIC) values as low as 0.
View Article and Find Full Text PDFFungal strains belonging to genus and are known to infect crops, resulting in threatened food security and less agricultural crop yields. The aim of the current work was to investigate the anti-mycotoxigenic activity, cytotoxic effect and antioxidant potential of selected South African medicinal plants extracts. The aqueous and organic extracts of the leaves from selected medicinal plants were investigated for their antifungal activity against various fungal strains that are known to infect crops and produce mycotoxins.
View Article and Find Full Text PDFBackground: Tuberculosis is counted amongst the most infectious and lethal illnesses worldwide and remains one of the major threats to human health. The aim of the current study was to isolate and characterize anti-mycobacterial compounds present in Curtisia dentata (Burm.f.
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