Publications by authors named "P M Danion"
Article Synopsis
- * In total, 36 patients were treated with a single local injection, and results showed that 47.2% achieved clinical remission at 24 weeks, while 41.6% achieved combined remission.
- * These findings suggest that approximately half of the patients had a successful response to darvadstrocel therapy in a real-world setting, indicating its potential effectiveness for treating this condition.
Background: Several studies have reported low levels of physical activity (PA) in patients with inflammatory bowel diseases (IBD), possibly related to a lack of information and support, despite the many recognized benefits such as cardiovascular prevention or quality of life (QoL) improvement.
Methods: The purpose of our study was to identify challenges faced by patients and to evaluate IBD impact on PA and QoL by using the International Physical Activity Questionnaire short form and the 32-item Inflammatory Bowel Disease Questionnaire (IBDQ-32) questionnaire, respectively. We also assessed the expectations and knowledge of patients and healthcare professionals using the MICI-Active questionnaire that we developed.
Background/aims: In Crohn's disease (CD) few data are available on the usefulness of monitoring fecal calprotectin (FC) in the early postoperative setting. We assessed prospectively the accuracy of FC measured 3 months after surgery to predict the risk of endoscopic postoperative recurrence (POR) within 1 year after resection.
Methods: In 55 consecutive CD patients who had undergone ileocolonic resection samples were collected 3 months after surgery for measuring serum CRP and FC.
Ustekinumab is approved for treatment of Crohn's disease (CD). Few data are available to assess the usefulness of monitoring inflammatory biomarkers and therapeutic drug monitoring to predict response to ustekinumab. We conducted a prospective study to assess the relationships between these parameters and the clinical outcome at week 16 in active CD patients receiving ustekinumab.
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- The study developed a self-questionnaire, called IBD-INFO, to evaluate patients' understanding of inflammatory bowel disease (IBD) and its treatment.
- The questionnaire was validated with both non-IBD volunteers and IBD patients, showing strong reliability and consistency in scores.
- The results indicated that knowledge was generally low among IBD patients, particularly in areas like vaccination, related cancers, treatments, and pregnancy, with specific factors identified that contributed to lower knowledge scores.