Publications by authors named "P M C Torres"
Blood pressure control with active ultrafiltration measures and without antihypertensives is essential for survival in hemodiafiltration and hemodialysis programs for patients with CKD: a prospective observational study.
BMC Nephrol
January 2025
Background: High blood pressure is a prevalent condition in patients with chronic kidney disease on hemodialysis. Adequate control of high blood pressure is essential to reducing deaths in this group. The present study aimed to observe mortality prospectively in a group of patients in hemodialysis and hemodiafiltration programs in whom the use of antihypertensives was optimized with the point-of-care dry weight (POC-DW) technique.
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- Recent studies highlight histatins, a group of salivary peptides, as effective agents in promoting wound healing in various tissues, notably skin, oral mucosal, and bone.
- Histatin-1, in particular, is recognized for its ability to enhance angiogenesis by facilitating endothelial cell functions, making it a key player in regenerative medicine.
- Despite promising therapeutic potential, there is still a lack of understanding regarding the precise molecular mechanisms through which histatin-1 induces these effects, underscoring the need for further research in this area.
Objective: Finely regulated Ghrelin (Ghrl) secretion is essential during early pregnancy, as infra or supraphysiologic levels can be detrimental. Since oestrogens stimulate Ghrl synthesis, ovarian stimulation (OS) might increase ghrelinemia, thus being detrimental for fertility. The aim of this work was to evaluate whether OS increases ghrelinemia and associates with maternal endocrine and immune biomarkers and reproductive success.
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- * A new online portal has been developed to provide up-to-date global distribution data for crayfish and their pathogens, improving accessibility and management decisions.
- * This database is publicly available, allowing users to easily view, embed, and download data, aiming to enhance conservation planning and biodiversity management in the future.
Article Synopsis
- - Amyotrophic lateral sclerosis (ALS) is a severe motor neuron disease with about a three-year average survival time, primarily characterized by TDP-43 protein issues that affect gene stability and autophagy processes.
- - Research on ALS mice revealed that reducing ATG4B worsens survival and autophagy, while an increase in LC3ylation was observed in both ALS patients and mouse models, suggesting a link between these processes.
- - Antisense oligonucleotides (ASOs) targeting TDP-43 genes have been developed, showing potential for non-invasive treatments that can effectively distribute in the brain after administration.