Unlocking the bitter potential of nostalgia: Covariation between and causal effects of nostalgia on envy.

Nostalgia is a sentimental longing for the past that is experienced across people from various cultures and across the lifespan. Though nostalgia has typically been conceptualized as a mixed emotion, prior research has primarily focused on positive effects. We hypothesized that nostalgia can additionally have certain negative effects.

Fine-tuning levels of filamins a and b as a specific mechanism sustaining Th2 lymphocyte functions.

Augmenting the portfolio of therapeutics for type 2-driven diseases is crucial to address unmet clinical needs and to design personalized treatment schemes. An attractive therapy for such diseases would consist in targeting the recruitment of T helper 2 (Th2) lymphocytes to inflammatory sites. Herein, we show the degradation of filamins (FLN) a and b by the ASB2α E3 ubiquitin ligase as a mechanism sustaining Th2 lymphocyte functions.

Six personas to adopt when framing theoretical research questions in biology.

Theory is a critical component of the biological research process, and complements observational and experimental approaches. However, most biologists receive little training on how to frame a theoretical question and, thus, how to evaluate when theory has successfully answered the research question. Here, we develop a guide with six verbal framings for theoretical models in biology.

Between common responsibility and national interest: When do Europeans support a common European migration policy?

The European Union has progressively communitarised its migration policy. The formation of public support for this integration of a core state power presents an intricate puzzle. On the one hand, immigration is part and parcel of the conflict around the opening and closing of nation states, and thereby mobilises nativist views and Euroscepticism.