From prediction to explanation: Is the relationship between youth psychopathy traits and continued offending in adulthood mediated by social environment?

Studies that focus on whether psychopathy statistically predicts reoffending are not informative of the process that connects the putative cause (psychopathy) to the expected outcome (offending). Understanding the causal mechanisms responsible for the relationship between psychopathy and offending has received minimal empirical attention even though fourth-generation risk assessment protocols and treatment strategies regularly require a specific focus on psychopathy. Theory can help guide an improved understanding of the causal mechanisms underlying the relationship between psychopathy and offending.

Circulating monocytes upregulate CD52 and sustain innate immune function in cirrhosis unless acute decompensation emerges.

Background & Aims: Infectious complications determine the prognosis of cirrhosis patients. Their infection susceptibility relates to the development of immuneparesis, a complex interplay of different immunosuppressive cells and soluble factors. Mechanisms underlying the dynamics of immuneparesis of innate immunity remain inconclusive.

Significant nocturnal wakefulness after sleep onset in metabolic dysfunction-associated steatotic liver disease.

Metabolic dysfunction-associated steatotic liver disease (MASLD) is a multisystemic disease with a multifactorial pathogenesis involving dietary, environmental, and genetic factors. Previous mouse models suggested that circadian misalignment may additionally influence its development as it influences metabolism in diverse organs including the liver. Further, data from sleep questionnaires proved sleep-wake disruption in patients with MASLD.

Sex Offender Recidivism: Some Lessons Learned From Over 70 Years of Research.

Sex offender recidivism (SOR) has been the subject of research for over 70 years. Myths, misconceptions, and erroneous conclusions about SOR, however, remain widespread, impeding the development of evidence-based policies aimed at preventing sexual offenses. To address the rich but uneven literature, a comprehensive review was conducted making it possible to provide a contextualized overview of scientific knowledge against the backdrop of methodological issues, challenges, and shortcomings.

A meta-analysis of trends in general, sexual, and violent recidivism among youth with histories of sex offending.

Recent research suggests that sexual recidivism rates have been declining, which contrasts with observations regarding general recidivism rates as well as perceptions of sexual reoffending risk. If sexual recidivism rates are in decline, it raises fundamental policy questions about the youth justice system's tendency to operate on the assumption that juvenile sexual offending is a risk marker for sexual reoffending in adulthood. A systematic review and a quantitative meta-analysis were conducted to determine the general, violent, and sexual recidivism rates of adolescent perpetrators of sexual offenses with data stemming from studies published worldwide between 1940 and 2019.