Publications by authors named "P Loubieres"
The aim of this study was to analyze the link between periodontal microbiota and obesity in humans. We conducted a cohort study including 45 subjects with periodontitis divided into two groups: normo-weighted subjects with a body mass index (BMI) between 20 and 25 kg/m ( = 34) and obese subjects with a BMI > 30 kg/m ( = 11). Our results showed that obesity was associated with significantly more severe gingival inflammation according to Periodontal Inflamed Surface Area (PISA index).
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- * Advanced statistical techniques were applied to analyze liver samples, revealing that a large proportion of early-stage fibrosis taxa belonged to families like Enterobacteriaceae and Pseudomonadaceae, while specific microbial pathways were linked to different fibrosis scores.
- * The findings suggest that bacteria may contribute to fibrosis progression, particularly in its early stages, and highlight the effectiveness of improved statistical methods to analyze microbiota data despite varying sample sizes and origins.
(1) Background: In developed countries, the prevalence of apical periodontitis (AP) varies from 20% to 50% for reasons that could be associated with the apical periodontitis microbiota ecology. (2) Methods: We performed a clinical study in the Odontology department of Toulouse hospital in France, to sequence the 16S rRNA gene of AP microbiota and collect clinical parameters from 94 patients. Forty-four patients were characterized with a PAI (periapical index of AP severity) score lower or equal to 3, while the others had superior scores (n = 50).
View Article and Find Full Text PDFThe oral cavity is host to a complex and diverse microbiota community which plays an important role in health and disease. Major oral infections, i.e.
View Article and Find Full Text PDFThe aim of this study was to analyze the link between oral microbiota and obesity in humans. We conducted a pilot study including 19 subjects with periodontitis divided into two groups: normo-weighted subjects (NWS) with a body mass index (BMI) between 20 and 25 ( = 9) and obese subjects (OS) with a BMI > 30 ( = 10). Obesity was associated with a poor oral health status characterized by an increased number of missing teeth and a higher score of periodontal-support loss associated with dysbiotic oral microbiota (39.
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