To be or not to be on: aspirin and coronary artery bypass graft surgery.

Aspirin's role in secondary prevention for patients with known coronary artery disease (CAD) is well established, validated by numerous landmark trials over the past several decades. However, its perioperative use in coronary artery bypass graft (CABG) surgery remains contentious due to the delicate balance between the risks of thrombosis and bleeding. While continuation of aspirin in patients undergoing CABG following acute coronary syndrome is widely supported due to the high risk of re-infarction, the evidence is less definitive for elective CABG procedures.

Ternary logic in the optical controlled-SWAP gate based on Laguerre-Gaussian modes of light.

The need set by a computational industry to increase processing power, while simultaneously reducing the energy consumption of data centers, became a challenge for modern computational systems. In this work, we propose an optical communication solution, that could serve as a building block for future computing systems, due to its versatility. The solution arises from Landauer's principle and utilizes reversible logic, manifested as an optical logical gate with structured light, here represented as Laguerre-Gaussian modes.

Prehabilitation before general surgery: Worth the effort?

Prehabilitation, or interventions before surgery aimed at improving preoperative health and postoperative outcomes, has various forms. Although it may confer benefit to patients undergoing general surgery, this is not certain. Furthermore, although it may yield a net monetary gain, it is also likely to require substantial monetary and non-monetary investment.

Physiological arousal underlies preferential access to visual awareness of fear-conditioned (and possibly disgust-conditioned) stimuli.

Fear and disgust have been associated with opposite influences on visual processing, even though both constitute negative emotions that motivate avoidance behavior and entail increased arousal. In the current study, we hypothesized that (a) homeostatic relevance modulates early stages of visual processing, (b) through widespread physiological responses, and that (c) the direction of these modulations depends on whether an emotion calls for immediate regulatory behavior or not. Specifically, we expected that increased arousal should facilitate the detection of fear-related stimuli, and inhibit the detection of disgust-related stimuli.

Enough blanket metaphysics, time for data-driven heuristics.

Bruineberg and colleagues criticisms' have been received but downplayed in the free energy principle (FEP) literature. We strengthen their points, arguing that Friston blanket discovery, even if tractable, requires a full formal description of the system of interest at the outset. Hence, blanket metaphysics is futile, and we postulate that researchers should turn back to heuristic uses of Pearl blankets.