Publications by authors named "P Lesprit"
Objectives: This study aimed to assess the frequency of co-resistance to antibiotics recommended in acute pyelonephritis among Escherichia coli clinical strains isolated from urinary tract infections (UTIs) acquired in community or nursing homes (NHs), and to identify situations without alternatives to fluoroquinolones (FQs).
Methods: All antimicrobial susceptibility test (AST) results of E. coli culture-positive urine samples from females living in the community or in NHs, collected through a large network of clinical laboratories in 2020 in France, were included.
HOSPITAL ANTIMICROBIAL STEWARDSHIP. Hospital antimicrobial stewardship programs have been thought to preserve the efficacy of antimicrobials for the treatment of human and animal bacterial infections. They must apply for every patient regardless of the type of healthcare facility- large or small, urban or rural, academic or community.
View Article and Find Full Text PDFIn the presence of a positive preoperative urine culture, the prescription of a preoperative antibiotic therapy is recommended. The choice of antibiotic therapy and prescription are usually made by the urologist or the general practitioner (GP). The objective of the treatment is urinary sterilization rather than parenchymal treatment, and the treatment choice is key to reduce selective pressure and antimicrobial resistance.
View Article and Find Full Text PDFArticle Synopsis
- In March 2020, the International Working Group on the Diabetic Foot published updated guidelines on diabetic foot infections, which were endorsed by the French ID society, SPILF, prompting them to revise their own 2006 guidelines.
- The new recommendations focus on microbiological diagnosis, antibiotic treatment options, and emphasize a multidisciplinary approach for managing diabetic foot infections.
- Key points include the necessity of staging the infection severity, proper sampling protocols, tailored empirical antibiotic therapy based on infection grade, and the importance of reevaluating treatment duration, especially when osteomyelitis is suspected.