Publications by authors named "P Leake"

Objective: We aimed to understand how, why and in what context upskilling programmes for unregulated care providers (UCPs) to provide foot screening for systematically marginalised groups living with diabetes were implemented.

Design: We used realist synthesis based on Realist And Meta-narrative Evidence Syntheses: Evolving Standards guidance.

Data Sources: We searched the Medline, Embase, PsycINFO, CINAHL, ERIC, Web of Science Core Collection, and Scopus databases and the grey literature (Google Scholar, ProQuest Dissertations and Theses) up to November 2022.

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Introduction: Foot ulcers are one of the most devastating complications of diabetes mellitus leading to leg amputations. In Canada, systematically marginalised and racialised populations are more prone to developing foot ulcers and at higher risk of limb amputations. Shortages of regulated healthcare have hindered efforts to provide foot care.

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Aim: Factors associated with verified post-colonoscopy colorectal cancers (PCCRC) have not been well defined and survival for these patients is not well described. We aimed to assess the association of patient, tumour and endoscopist characteristics with PCCRC.

Methods: Using population-based data, we identified individuals diagnosed with CRC from 1 January 2000 to 31 December 2005 who underwent a colonoscopy within 3 years prior to diagnosis.

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Article Synopsis
  • Hearing impairment is a significant global health issue, and cochlear implants (CIs) are the main treatment for severe hearing loss, though outcomes vary greatly among users, particularly in children.
  • Recent research is focused on improving the survival of auditory nerve cells (spiral ganglion neurons) after deafness, notably using neurotrophic factors (NTs) like Brain-Derived Neurotrophic Factor (BDNF) in animal studies.
  • NT gene therapy shows potential for providing long-term benefits by encouraging natural NT production in the cochlea, but challenges remain regarding treatment methods and delivery before it can be applied in clinical settings.
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Objective: Colorectal carcinoma (CRC) is the third most common cancer and a leading cause of cancer-related deaths in Jamaica. Globally, CRC mortality rates have been decreasing in developed countries; however, CRC mortality rates are trending upwards in low-income or developing countries. Our objectives are to estimate the overall 5-year survival and to determine the pathologic factors associated with overall survival of colorectal adenocarcinoma after surgery at the University Hospital of the West Indies (UHWI).

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