Publications by authors named "P Le Turnier"

Objectives: HIV viral load set points may vary between virus subtypes and host characteristics. The HIV epidemic in French Guiana entails a mix of viruses and populations of cosmopolitan origins. In this epidemiological context, we aimed to determine whether, at the scale of our territory, we could identify differences in HIV-1 viral load setpoints in our hospital cohort.

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  • - Predicting outbreaks of infectious diseases requires interdisciplinary research that focuses on how diseases are transmitted and experienced, emphasizing the role of diverse species beyond just vertebrates.
  • - Current understanding of mycobacterial diseases is mainly based on studies of infections in vertebrates, but new literature suggests a need to consider interactions with non-vertebrate organisms that could shape disease transmission and risk.
  • - The findings challenge prevailing theories of human transmission and advocate for an ecological and evolutionary approach, offering new perspectives on disease prevention and management strategies.
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  • In 2022, four severe cases of Hantavirus pulmonary syndrome (HPS) were reported in informal settlements in French Guiana, prompting a study to estimate the prevalence of Hantavirus infections in the area.
  • The French Red Cross trained health mediators to support the investigation, leading to increased awareness and participation from local residents, with over 90% indicating their willingness to partake in the study.
  • The study found a 5.1% positivity rate of IgG anti-Hantavirus among participants, highlighting the effectiveness of the mediators' involvement in the health awareness and data collection process.
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The drivers of the HIV epidemic, the viruses, the opportunistic infections, the attitudes and the resources allocated to the fight against HIV/AIDS, vary substantially across countries. French Guiana, at the crossroads between Amazonian South America and the Caribbean, constitutes a singular context with poor populations and rich country health funding, which has allowed researchers to gather lots of information on the particulars of our epidemic. We aimed to focus on the little known story of forty years of HIV research in French Guiana and emphasize how local research intertwined with public health action has yielded continuous progress, despite the difficult social conditions of the affected population.

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Objectives: The empirical treatment of infective endocarditis is still debated. The aim of this study was to compare the impact of empirical treatment with antistaphylococcal penicillin (ASP) or cefazolin vs. other treatments in methicillin-susceptible Staphylococcus aureus (MSSA) endocarditis.

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