Local chest wall progression of chemotherapy/radiation-resistant breast cancer can result in substantial morbidity. In this retrospective review of 39 patients in this difficult clinical setting treated at Cancer Treatment Centers of America (Eastern Regional Medical Center), approximately one-half of the population experienced meaningful short-term palliation and improvement in quality of life when managed with local superficial hyperthermia plus external beam radiation.
View Article and Find Full Text PDFThe aim of this paper is to supplement the GEC/ESTRO/EAU recommendations for permanent seed implantations in prostate cancer to develop consistency in target and volume definition for permanent seed prostate brachytherapy. Recommendations on target and organ at risk (OAR) definitions and dosimetry parameters to be reported on post implant planning are given.
View Article and Find Full Text PDFArch Ital Urol Androl
December 2002
Unlabelled: The rationale for interstitial brachytherapy (seed implant) is based on the principle that dissipation of radiation energy in tissues decreases exponentially as the square of source would receive maximal doses of radiation, there will be a rapid fall-off the dose in surrounding normal tissues. Over the years, a range of isotopes have been tested, and the technique have evolved from free-hand implantation to ultrasound guided template system.
Materials And Methods: From September 2001 to March 2002 we treated 17 patients with clinically localized prostatic cancer.
Among women with node-negative breast cancer and small tumours, it is important to identify those with tumours that will recur, so that they may receive adjuvant therapy, while sparing those with tumours that will not recur the hazards of adjuvant treatment. A reverse transcriptase-polymerase chain reaction (RT-PCR) for prostate-specific antigen (PSA) may be used to identify circulating metastatic cells in patients with prostate cancer. Approximately 30% of breast cancer cells also produce PSA.
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